Fitness

Anabolic Steroids for Muscle Growth: Side Effects and Risks

Anabolic steroids can increase muscle size, but that does not establish safety. Understand the health risks, what recovery evidence actually shows, and how to discuss use without judgement.

By Vitalo EditorialPublished Updated 15 min read
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The short answer

Non-medical anabolic steroid use can suppress natural hormone production, impair fertility and cause other physical and psychological harms. Research also links use with cardiovascular disease. Risks vary by substance, exposure and personal circumstances; a muscular appearance or normal blood test does not establish safety. Prescribed testosterone for a diagnosed condition is a different clinical situation. If you use steroids or want to stop, seek individual medical support rather than relying on a cycle or recovery protocol found online.

What are anabolic steroids?

Anabolic-androgenic steroids, often shortened to AAS, are substances related to testosterone. The name describes effects on tissue growth and androgen-related characteristics. Testosterone itself is an anabolic-androgenic steroid; not every substance sold for physique or performance enhancement belongs to this class.

Some have legitimate medical uses. This guide focuses on use without an appropriate prescription or outside the prescribed treatment plan for muscle building or appearance. It explains risks and questions to take to a healthcare professional, rather than recommending a drug, dose or course of treatment.

References 1 2

Which symptoms need urgent medical help?

Call your local emergency service for suspected heart-attack symptoms, such as chest pressure or pain with breathlessness, or stroke symptoms such as sudden facial weakness, arm weakness or difficulty speaking. Do not wait for a routine appointment or a reply on a fitness forum.

Yellow skin or eyes, dark urine or significant abdominal pain need prompt medical assessment. If your mental state makes it difficult to stay safe, seek emergency help. Tell the treating team about medicines, supplements and any non-prescribed products you have taken; bring packaging or a clear photo if available.

References 9 13 19 20 21

Do anabolic steroids actually increase muscle growth?

They can. A controlled trial in healthy men demonstrated increases in muscle size and strength with testosterone exposure above normal physiological levels, especially alongside resistance training. Acknowledging that effect is important: telling readers these drugs do nothing would misrepresent the evidence.

A short trial showing a muscle-building effect does not establish the safety of prolonged use, combinations of substances or products from informal suppliers. The possibility of faster gains and the possibility of serious harm can both be true. Transformation photos cannot provide the missing safety information.

References 3

Anabolic steroids, prescribed testosterone and corticosteroids are different questions

The word “steroids” is ambiguous. Corticosteroids used for inflammatory conditions are a different drug class from anabolic steroids. Do not stop a prescribed asthma, inflammatory-disease or hormone medicine because you have read about bodybuilding-related risks; discuss concerns with its prescriber.

For men being assessed for testosterone deficiency, the Endocrine Society requires a clinical assessment and consistently low, accurately measured testosterone alongside compatible symptoms or signs. A training plateau, tiredness or a single result does not by itself establish the diagnosis.

Medical testosterone treatment still needs monitoring. In 2025, the US FDA removed cardiovascular-risk language from the boxed warning for testosterone products after reviewing the TRAVERSE trial, while requiring blood-pressure warnings. That update concerns prescribed treatment evidence; it does not establish the safety of non-medical anabolic steroid use.

SituationImportant distinction
Non-medical AAS useMuscle-building or appearance use outside an appropriate treatment plan; risks cannot be inferred from a prescribed-treatment trial.
Prescribed testosterone treatmentTreatment for an assessed medical indication, with an individual benefit–risk discussion and follow-up.
CorticosteroidsA different class used for conditions such as inflammation; follow the prescriber’s instructions.
References 1 4 5 18

Anabolic steroid side effects: a practical overview

Effects depend on the substance, exposure, other products used and individual health. The table organises possible concerns; it is not a prediction that every person will develop every problem. Some changes are noticeable, while other problems require clinical assessment.

AreaExamples of concerns
Heart and circulationRaised blood pressure, adverse cholesterol changes and associations with serious cardiovascular disease.
Hormones and fertilitySuppression of natural hormone signalling, reduced sperm production and menstrual changes.
Liver and kidneysDrug-related liver injury; kidney concerns that need individual investigation.
Skin and appearanceAcne, hair loss and androgen-related hair growth or voice changes.
Mood and dependenceMood disturbance, dependence and withdrawal symptoms.
Injection and product qualityInfection, blood-borne virus exposure and uncertainty about ingredients or strength.
References 10 12 21

What does research show about heart and cardiovascular risks?

A Danish cohort study published in Circulation in 2025 compared 1,189 men sanctioned for AAS use with 59,450 matched men from the general population. Over approximately eleven years, AAS use was associated with higher rates of several outcomes, including heart attack, heart failure and cardiomyopathy, a disease of the heart muscle.

A separate 2025 study examined cardiovascular findings in male and female recreational athletes. Greater cumulative exposure was associated with adverse findings and impaired ventricular function. It was a smaller cross-sectional study: it cannot establish the sequence of events or predict an individual’s future outcome.

A 2024 mortality study also found higher mortality in a Danish AAS-user cohort. These are observational findings, and differences between groups and other exposures can influence the results. They should not be presented as an exact personal risk or as evidence that every user will develop heart disease. They do strengthen the case for taking cardiovascular concerns seriously.

References 6 7 8

Hormones, testosterone suppression and male fertility

Externally supplied androgens can suppress the body’s reproductive hormone signalling. In men, consequences can include reduced sperm production, smaller testicular size and impaired fertility. A high circulating androgen level during use does not mean normal sperm production is being maintained.

Reduced libido, erectile difficulties or fatigue after stopping need assessment rather than an assumption that one extra medicine will solve the problem. If having children matters to you now or later, raise that explicitly with a clinician. A blood testosterone result alone does not measure fertility.

References 10 11 18

Side effects in women and additional concerns for adolescents

Women can experience menstrual disruption and androgen-related changes such as increased facial or body hair, a deeper voice and clitoral enlargement. Some changes may persist after use stops. A lower exposure or a product advertised for women is not assurance that these effects will be avoided.

Adolescents have additional developmental concerns, including premature closure of growth plates and restricted height growth. Evidence from adult bodybuilding populations should not be used to declare a product safe for a teenager. A young person worried about physique, performance or exposure deserves confidential, age-appropriate professional support.

References 1 2 12 21

Liver injury, kidney concerns and why the formulation matters

LiverTox describes several forms of liver injury associated with androgenic steroids. Certain chemically modified oral steroids are particularly associated with cholestasis, where bile flow is impaired. Itching, dark urine and jaundice can occur, and recovery may be prolonged.

That does not mean every formulation has the same liver-risk profile, or that avoiding tablets makes non-medical use safe. Other cardiovascular, hormonal, product-quality and injection risks remain. Kidney symptoms or abnormal test results also need clinical interpretation, including the context of training, other substances and existing illness.

Do not use a “liver support” supplement or a normal enzyme reading as proof that a product is harmless. LiverTox notes that substantial steroid-related cholestasis may occur with only modest enzyme elevations. Symptoms and the full clinical picture matter.

References 9 21

Mood, body image, dependence and withdrawal

Non-medical AAS use can be accompanied by mood and behavioural changes. Dependence can develop, and coming off can involve anxiety or depression. These concerns deserve care; they should not be reduced to a stereotype that every person using steroids is aggressive.

Fear of losing muscle or confidence can make it difficult to reduce use or ask for support. A non-judgemental conversation can cover body-image pressure as well as physical symptoms. Tell a clinician if changes in mood, sleep or relationships are becoming difficult to manage.

References 2 10 21

Injection risks are separate from the drug’s effects

Injecting introduces additional risks, including local infection and exposure to blood-borne viruses through shared equipment. CDC guidance identifies shared needles, syringes and other injection equipment as routes for hepatitis C transmission.

Never share injection equipment. A local needle-and-syringe or harm-reduction service can advise about sterile equipment, disposal and testing. This reduces particular risks; it does not remove the hormonal or cardiovascular effects of the drug. Seek medical assessment for a painful, red or swollen injection site, especially with fever.

References 15 21

Do cycling, stacking or “mild” steroids make use safe?

“Cycling” refers to periods of use and non-use; “stacking” means combining substances. The NHS states that there is no evidence these approaches reduce the side effects and harms associated with anabolic steroids. They should not be described as proven protection.

A product being called “mild”, “beginner-friendly” or “natural” is a marketing description, not a clinical safety finding. Neither an absence of visible changes nor a suggested online routine establishes a safe exposure.

References 2 13

SARMs and bodybuilding products are not automatically safer alternatives

Selective androgen receptor modulators, or SARMs, are not the same drug class as anabolic steroids. The US FDA warns that products marketed as containing SARMs are unapproved drugs, not legitimate dietary supplements, and have been associated with serious harms including liver injury.

Product identity is another uncertainty. In a 2026 advisory, Australia’s TGA reported that testing of specific unapproved products found substantially less active ingredient than the label stated. That finding applies to the tested products; it is not a measurement of every online product.

An attractive label, “research use only” wording or online availability does not establish quality or safety. Tell a healthcare professional about the actual products you have used, including things you considered supplements.

References 13 14

What happens after stopping anabolic steroids?

Recovery is variable. A 2023 scoping review found that hormonal, reproductive, physical and psychological outcomes follow different time courses, with limited prospective evidence. It does not support promising that everyone’s testosterone or fertility will be normal by a fixed date.

Some functions improve over time, while some physical changes may persist. Normalisation of one hormone result does not prove that fertility, mood and cardiovascular health have all recovered. Follow-up should address the symptoms and goals that matter to the person.

If you want to stop, contact a healthcare professional for an individual plan. Withdrawal can be difficult, and self-prescribed “post-cycle therapy” adds medicines with their own risks. Clinical reviews discuss treatment in selected situations; that is not evidence for a universal do-it-yourself protocol. Do not change an existing prescribed treatment without speaking to its prescriber.

References 10 11 21

How to prepare for a healthcare appointment

You do not need to arrive with the perfect explanation or wait for an obvious complication. Start with what you used, your concerns and whether you want help stopping. NSW Health recommends asking about AAS use without judgement and assessing physical and mental health together.

The clinician may consider blood pressure, blood counts, cholesterol, liver and kidney measures, reproductive hormones or other investigations based on your history. This is not a universal test panel or a schedule for self-monitoring; normal results cannot certify continued use as safe.

  • Bring product names, packaging or photos, and a record of when you used them.
  • List prescribed medicines, other non-prescribed drugs and supplements.
  • Describe physical symptoms, sleep and mood changes, and any injection-site problems.
  • Mention fertility plans, pregnancy possibility and concerns about stopping.
  • Ask what needs follow-up, who to contact if symptoms change and what confidentiality rules apply locally.
References 12 21

International readers: separate medicines rules from sport rules

Prescription, supply and import rules differ between countries and sometimes between regions. US FDA approval statements and Australian TGA advisories apply to their respective jurisdictions. Check your own medicines regulator and travel requirements; availability from an online seller is not legal or medical clearance.

For athletes subject to the World Anti-Doping Code, anabolic agents are prohibited in and out of competition under the 2026 WADA List. Check the list in force for the relevant date. A prescription is not automatically a Therapeutic Use Exemption: discuss any TUE requirements with the responsible anti-doping organisation. Emergency treatment should not be delayed for paperwork.

References 13 14 16 22

Can you build muscle without anabolic steroids?

Yes. Progressive resistance training is an evidence-based way to improve strength and muscle size in healthy adults. ACSM’s 2026 overview supports regular training with an appropriate progression; it does not make non-medical anabolic steroid use a requirement.

If progress seems slow, first review a consistent training record and the basics of nutrition and recovery. Vitalo’s seven-check guide helps organise that review. It cannot diagnose a hormone problem or assess damage from a drug.

Why am I not building muscle? Seven things to check

References 17

Keep everyday nutrition tools in their proper role

For general fitness planning, Vitalo’s protein calculator offers an estimated range to discuss alongside your eating pattern. It is not a steroid-support, detox or recovery tool and cannot make non-medical use safe. Medical conditions or a prescribed nutrition plan need individual guidance.

Choose a sustainable routine, with support where needed

A beginner routine should fit your experience, equipment and recovery. Use the workout library to read the scope of a plan before starting; if you have symptoms or concerns about AAS exposure, obtain appropriate medical advice rather than using a new routine as treatment.

Keep goals specific and manageable: a repeatable training schedule, reliable meal records and a useful next check-in. Your health and confidence deserve attention alongside performance. A change in muscle size is not a measure of your worth.

Explore Vitalo’s beginner workout library

How this guide was prepared and what remains uncertain

Prepared by Vitalo Editorial from the studies, clinical reviews and official resources listed below, checked on 30 October 2026. The guide distinguishes controlled evidence of muscle-building effects from observational evidence of longer-term harms. Group findings do not calculate an individual’s risk.

The resource selection includes international anti-doping guidance, UK and Australian public-health information, US regulatory and endocrine guidance, and clinical research. Regulations, approved indications and access to care differ locally. The article is general education, not a personal treatment plan, and has not been independently clinically reviewed. The cited organisations do not endorse Vitalo.

Put it into practice

A useful next step

Frequently asked questions

What are the main anabolic steroid side effects?

Concerns include hormone suppression, impaired fertility, acne, mood changes, liver injury and cardiovascular problems. The risk and severity vary; a list of possible effects is not a prediction for every person. See sources 9, 10 and 21.

Are anabolic steroids the same as corticosteroids?

No. Corticosteroids used for inflammatory conditions are a different drug class. Follow your prescription and discuss concerns with its prescriber rather than changing treatment because of a bodybuilding article. See source 1.

Is testosterone replacement therapy the same as bodybuilding steroid use?

Testosterone is an anabolic-androgenic steroid, but treatment for an assessed medical indication is a different clinical situation from non-medical use. Diagnosis, exposure and monitoring matter; prescribed treatment still has risks. See sources 4, 5 and 18.

Can anabolic steroids affect fertility?

Yes. They can suppress reproductive hormone signalling and sperm production, and menstrual function can also be disrupted. Recovery is variable. Discuss fertility goals with a clinician; a testosterone result alone does not assess fertility. See sources 10–12.

Are anabolic steroid side effects reversible?

Some effects improve after stopping, while others may persist. Hormones, sperm production, mood and physical changes have different recovery patterns. A fixed recovery deadline is not supported for everyone. See source 11.

Do cycling or stacking prevent steroid side effects?

No protective effect has been established. The NHS states there is no evidence that these approaches reduce the side effects and harms associated with anabolic steroids. See source 2.

Are SARMs a safe alternative to steroids?

They should not be presented as a safe substitute. The US FDA warns about serious harms and unapproved products, and product labels may not accurately describe contents. SARMs are a different class, not ordinary nutritional supplements. See sources 13–14.

Can normal blood tests prove steroid use is safe?

No. Testing can identify some concerns but cannot certify safety or exclude every complication. Assessment depends on symptoms, exposure, examination and follow-up. Liver-related symptoms can also occur with modest enzyme elevations. See sources 9 and 12.

Should I follow an online post-cycle therapy plan?

Use individual medical support instead of assuming an online drug protocol is appropriate. Recovery evidence is limited, withdrawal can be difficult and additional medicines have their own risks. See sources 10, 11 and 21.

Can I build muscle without steroids?

Yes. Progressive resistance training can improve strength and muscle size. Review training consistency, nutrition, recovery and the outcome you are measuring, without assuming slow progress diagnoses a hormone deficiency. See sources 4 and 17.

Sources & further reading

  1. 1.Healthdirect Australia — anabolic steroids, their medical role and adverse effects
  2. 2.NHS — anabolic steroid misuse, adverse effects, dependence and cycling claims
  3. 3.Bhasin et al., NEJM, 1996 — controlled trial of testosterone, muscle size and strength in men
  4. 4.Endocrine Society, 2026 — statement on testosterone replacement therapy and accurate diagnosis
  5. 5.US FDA, 2025 — updated testosterone labelling, TRAVERSE findings and blood-pressure warnings
  6. 6.Windfeld-Mathiasen et al., Circulation, 2025 — cardiovascular disease in male AAS users: cohort study
  7. 7.Buhl et al., JAMA Network Open, 2025 — cardiovascular status in male and female AAS users: cross-sectional study
  8. 8.Windfeld-Mathiasen et al., JAMA, 2024 — mortality among AAS users: Danish cohort study
  9. 9.NIH/NIDDK LiverTox — androgenic steroids and patterns of liver injury
  10. 10.Anawalt, JCEM, 2019 — clinical review of diagnosis and management of AAS use
  11. 11.Solanki et al., Endocrine Connections, 2023 — scoping review of recovery after steroid-induced hypogonadism
  12. 12.NSW Health — GP quick reference guide to AAS/PIED harm minimisation
  13. 13.US FDA — serious risks of bodybuilding products marketed with SARMs or steroid-like substances
  14. 14.Australian TGA, 2026 — laboratory findings on specific unapproved SARMs products
  15. 15.US CDC — hepatitis C prevention and blood-borne transmission through shared injection equipment
  16. 16.World Anti-Doping Agency — Prohibited List, updated annually; check the edition in force
  17. 17.Currier et al., ACSM Position Stand, 2026 — resistance training and muscle hypertrophy in healthy adults
  18. 18.Endocrine Society, 2018 — testosterone therapy in men with hypogonadism: clinical practice guideline
  19. 19.NHS — stroke symptoms and emergency action
  20. 20.NHS — heart attack symptoms and emergency treatment
  21. 21.Eu et al., Australian Journal of General Practice, 2026 — clinical harm-reduction approach to AAS and other PIEDs
  22. 22.International Testing Agency — Therapeutic Use Exemptions and emergency treatment

About the author

Vitalo Editorial

Vitalo Editorial creates practical guides to food, habits, and body measurements. Articles connect published health resources with worked examples and Vitalo tools. These guides provide general education; individual articles name a clinical reviewer only when an actual qualified review has taken place.

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